Collagene: cos’è, come preservarlo e tutti i benefici per la pelle

Collagen: what it is, how to preserve it, and all its benefits for the skin

| Scritto da Silvia Piccoli

Collagen is a fundamental protein for our body, forming the basis of the structure of skin, bones, muscles, and connective tissues. It ensures structure, compactness, and resistance, making it an indispensable ally for firm and youthful skin over time. As we age, however, its production physiologically decreases, leading to the appearance of signs of aging: loss of tone, wrinkles, and less firm skin.

But what can we do to preserve it, stimulate its synthesis, and contribute to more elastic, toned, and visibly healthy skin? In this article, we will discover what collagen is, why its production slows down over time, and what signs may indicate a deficiency. We will delve into the main factors that accelerate its loss and effective strategies to stimulate it naturally, through lifestyle, skincare, and professional treatments.

We will also explore Terme di Comano Skincare's proposals – from Signature Treatments to home products – designed to support collagen production and visibly improve skin quality. Finally, thanks to expert advice, we will answer the most common questions about skin aging, offering practical guidance for conscious and targeted skin care.

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What is collagen?

Collagen is the main structural protein in our body, an essential element that provides support, elasticity, and strength to tissues. Present in large quantities in the skin, bones, tendons, and cartilage, it acts as a true "biological scaffold," capable of maintaining the integrity of connective tissue structures.


In the dermis, in particular, it plays a crucial role: together with elastin and hyaluronic acid, it helps make the skin firm, toned, and visibly younger. Over time, however, the endogenous production of collagen physiologically tends to decrease, starting as early as 25 years of age, and this process accelerates with aging, exposure to UV rays, oxidative stress, and an unbalanced lifestyle.

The result? Skin that appears less elastic, thinner, and more marked, accompanied by increased fragility of connective tissues. For this reason, collagen has become one of the most sought-after active ingredients in cosmetics, nutraceuticals, and dermatology: supporting its presence, in fact, means promoting healthier, stronger, and visibly firmer-looking skin.

Collagen: essential benefits for skin, hair, joints, and overall well-being

When collagen is mentioned, it is often associated with skin and aesthetics. In reality, its role is much broader: this protein is an integral part of numerous tissues – skin, tendons, cartilage, bones, blood vessels – and ensures their structure, elasticity, and regenerative capacity.


With age, its production slows down, and the consequences become visible and perceptible: more pronounced wrinkles, loss of tone, brittle hair, less flexible joints. This is why targeted skincare, supplementation, and a conscious lifestyle are the most effective strategies for comprehensive self-care.

  • Collagen benefits for skin

    According to a meta-analysis published in 2023 (Effects of Oral Collagen for Skin Anti-Aging), regular intake of collagen peptides (i.e., smaller, more easily absorbed fragments of hydrolyzed collagen) has shown positive effects on skin tone, hydration, and density, even in subjects over 40.

    Specifically:

    • Stimulates the production of new endogenous collagen
    • Supports deep skin hydration
    • Promotes a uniform and compact texture
    • Visibly reduces signs of aging

  • Benefits of collagen for hair and nails

    Collagen is essential for the well-being of hair follicles and for keratinization, the process that gives structure and strength to hair and nails. With aging or in the presence of oxidative stress, follicles can weaken, leading to hair loss or premature graying.

    Proper supplementation can:

    • Strengthen hair structure and prevent hair loss
    • Counteract premature graying by acting on the hair bulb
    • Improve shine and resistance to damage
    • Strengthen nails, preventing flaking and breakage


    Some research has also highlighted the potential of collagen in counteracting the damaging effects of oxidative stress on the scalp, improving local microcirculation and nutrient absorption.

  • Benefits of collagen for joints, bones, and cartilage

    At the osteoarticular level, collagen constitutes the fibrous component of ligaments, cartilage, and joints. With age or following trauma, its degradation can cause joint pain, stiffness, and increased bone fragility.

    The regular intake of type II collagen (often from animal sources) is the subject of numerous studies, which suggest:

    A significant reduction in joint pain, even in subjects with arthritis or osteoarthritis

    • An improvement in joint mobility and flexibility
    • Greater resistance and regeneration of cartilage
    • Concrete support in post-traumatic or sports recovery processes


    Although the EFSA (European Food Safety Authority) has not yet approved specific claims for the use of collagen
    for therapeutic purposes, clinical interest in this protein is constantly growing, especially in the nutraceutical, dermatological, and orthopedic fields.

  • Supporting overall well-being

    In addition to its aesthetic and functional benefits, collagen also supports the health of blood vessels, gums, internal organs, and the gut microbiota. As a widespread structural protein, it helps maintain tissue integrity and their ability to withstand mechanical and inflammatory stress.

Why does the body reduce collagen production?

Despite its key role in keeping the body young and toned, the production of this protein does not remain constant over time. As we age, in fact, fibroblasts – the dermal cells responsible for its synthesis – progressively become less active. This change is linked to the natural process of cellular senescence, which reduces the body's ability to generate the structural proteins necessary to support tissue elasticity and compactness.


This process already begins around 25-30 years of age, when the body reaches its peak collagen production. From this age onwards, synthesis gradually begins to decline: after 35, the first signs may become evident with a progressive loss of skin tone and compactness. Around 40-50 years of age, the reduction becomes more pronounced, especially in women, who during menopause can lose up to 2% of collagen each year.


Its reduction has an impact on multiple levels: the skin loses elasticity, the first wrinkles appear, hair becomes more fragile, nails flake more easily, while bones, joints, and ligaments progressively become more vulnerable. Joint flexibility can also decrease, with an increased risk of pain or injury.

Factors that accelerate collagen loss

In addition to the physiological aging process, certain habits and external factors can accelerate collagen loss. Prolonged sun exposure without protection, smoking, a diet low in antioxidants, chronic stress, and lack of sleep are among the skin's primary enemies. These elements increase free radicals and trigger oxidative stress, which damages cellular structures, including collagen. Pollution and excessive sugar consumption also contribute to weakening its fibers, making the skin less elastic and more prone to wrinkles and sagging.

The good news is that today there are numerous strategies to counteract or slow down its loss, starting with an adequate skincare routine and extending to active prevention that involves nutrition, supplementation, and skin protection.


To learn more: Skin Aging: what it is, its causes, and remedies for young and healthy-looking skin

How to compensate for collagen loss

The progressive reduction of collagen in our body is a physiological process, but its effects are not inevitable. In fact, there are several simple, daily strategies that can help slow down this phenomenon and preserve the elasticity, firmness, and health of skin and connective tissues for longer.

The first ally is lifestyle: a varied and balanced diet is fundamental to naturally support production. Foods rich in vitamin C (such as citrus fruits, kiwis, peppers), zinc, copper, and essential amino acids (found in meat, fish, and eggs) promote the endogenous synthesis of this precious protein. Fruits and vegetables, with their antioxidant content, also help to counteract oxidative stress that accelerates collagen degradation.

Valuable support can come from specific supplements, particularly those based on hydrolyzed collagen, which is better absorbed by the body. Although there are no official claims approved by EFSA yet, several studies suggest a potential benefit in maintaining skin elasticity and supporting joints.

Alongside nutrition, skincare also plays an essential role. Using cosmetic products formulated with stimulating ingredients such as retinol, peptides, hyaluronic acid, and vitamin C can help improve skin hydration, tone, and resistance. Collagen can also be directly present in hydrolyzed form in creams or serums, visibly aiding the firming and plumping effect.

Finally, it is important to limit factors that accelerate collagen degradation: excessive sun exposure, smoking, alcohol, and chronic stress contribute to accelerating skin aging and loss of tone. Protecting the skin from UV rays with adequate sun protection and maintaining a healthy and active lifestyle are fundamental precautions to support the longevity of skin and tissues.

In summary, even though collagen production decreases with age, adopting a targeted and conscious care routine can make a difference in maintaining healthy, radiant, and resilient skin over time.

Comano Spa solutions

Collagen at the heart of our Signature Treatments

Terme di Comano has always guided the skin on a journey of deep regeneration, where sensoriality and concrete results meet to support elasticity, firmness, and radiance over time.
At the Thermal Spa, the Signature Treatments combine the regenerating power of Comano Thermal Water, known for its soothing and detoxifying properties, with excellent biotechnological active ingredients.

From anti-aging treatments such as Lifting Filler with Collagen Threads, which redefines the face and neck thanks to the synergy of collagen, stem cells, and a tightening mask, to the Global Longevity Anti-Aging protocol, which combines pure collagen with Kobido massage for a deep lifting effect: each treatment is designed to awaken the skin's vitality and strengthen its structure.

Even smart rituals like the Pure Collagen Mask with Wow Lifting effect, perfect for a special occasion, offer an instant boost of firmness and radiance. Not to mention the Illuminating Firming Treatment with Vitamin C, which stimulates collagen production by counteracting oxidative stress, and the Thermal Facial Cleansing, which prepares the skin for deep regeneration.

Each treatment is a promise of beauty and well-being, where nature, research, and manual skill merge to offer tangible results and a complete care experience.

For more information on Terme di Comano's Signature Treatments, click here.

Skincare products to promote collagen stimulation and firmness

Among the facial products is the Instant Revitalize Mask, a brightening and plumping treatment that harnesses the synergistic action of Hyaluronic Acid, Organic Barley Water, and Opuntia Ficus extract to promote the natural production of collagen, elastin, and hyaluronic acid. The result? Smooth, radiant, and visibly more elastic skin from the very first application.

To complete its anti-aging action, Terme di Comano Skincare offers advanced formulas with functional active ingredients capable of promoting collagen synthesis and acting on its degradation, improving the tonicity, volume, and definition of facial contours. This is the case with the Pro Multi-Perfection Filler Cream and the Vitamin C + Retinol Superconcentrated Serum, which combine gradual-release retinol with vitamins and biotechnological active ingredients to promote cellular renewal and support the skin structure.

Within the Global Age line, both the Rich Texture and Fresh Texture Creams represent a targeted treatment to counteract the signs of aging: plant stem cells, stabilized vitamin C, and hyaluronic acid work synergistically to improve skin firmness and restore its radiance.

The protocol is completed by the Eye and Lip Contour Cream, designed for the most delicate areas, which helps to smooth out signs of fatigue, reduce bags and dark circles, and restore definition to the eyes and smile.

For the body, the Saline No Cell Body Cream is the star of two targeted programs: the Drenactive Program – an intensive 30-day treatment – and the Light Legs Beauty Routine. Both protocols harness the draining action of sea salt and caffeine in combination with Comano Thermal Water to smooth the skin and boost the production of collagen and elastin, visibly improving skin texture.

To complete the firming action, the Velvety 3-in-1 Body Cream provides elasticity and tonicity thanks to microalgae extract, contributing to the strengthening of collagen fibers and resulting in compact and hydrated skin.

Each formula is designed to be gentle even on the most sensitive skin, confirming the brand's dermatological commitment to authentic beauty that respects the skin.

Collagen: our experts' advice

As already mentioned, the natural decline in collagen production is a physiological process, but it doesn't mean we have to passively accept it. With the right strategies, it's possible to counteract its effects, support skin vitality, and preserve its elasticity and radiance over time. The experts at Terme di Comano have compiled the most frequently asked questions on the topic and shared practical tips to consciously address age-related changes.

How to tell if you're lacking collagen?
One of the first signs is the early appearance of wrinkles, loss of skin tone, and increased skin fragility. Joint pain, stiffness in movements, or a feeling of less toned muscles can also be symptoms linked to a lower presence of collagen.


At what age does collagen begin to decrease?
There is no precise age: each body has its own timeline. However, research indicates that the peak is reached between 25 and 35 years old, followed by a gradual reduction. From age 35 onwards, the first visible signs may appear: wrinkles, fine lines, loss of firmness. Around 40-50 years old, especially coinciding with menopause, the loss accelerates to up to 2% per year.


Why does the body stop producing collagen?
With aging, cells become less efficient: cellular senescence slows down the production of structural proteins like collagen, and fibroblasts – the cells that produce it – become less active. External factors such as smoking, stress, sun exposure, and an unbalanced diet can also worsen the situation.

Conclusion

Skin care is not just an aesthetic gesture, but an act of prevention and awareness. Targeted skincare, professional treatments, and healthy lifestyle habits can slow down the signs of aging and support natural collagen production. Consistency makes all the difference.

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