LYSACOM BIOME™: THE ACTIVE INGREDIENT FROM COMANO THERMAL WATER

An exclusive and patented ingredient in Italy, the result of 10 years of research and innovation on Comano Thermal Water and the essential microorganism of its microbiota: Mesorhizobium Comanense .

An innovative active ingredient with proven efficacy and extraordinary anti-inflammatory, soothing and softening properties.

FROM ​MESORHIZOBIUM COMANENSE TO THE LYSATE:
SCIENTIFIC RESEARCH

Studies* on the application of lysates in the dermatological field are recent and have demonstrated the ability to have regenerative effects on the skin with complete restoration of all skin layers, increasing the skin barrier function.

Starting from these results, we thought of obtaining a bacterial lysate from the Mesorhizobium comanense of the Comano Thermal Water.

The Lysacom Biome™ bacterial lysate from Comano Thermal Water - patented in Italy, was produced by the Department of Computational and Integrated Cellular Biology (CIBIO) of the University of Trento.

Once the bacterial lysate was obtained in the laboratory and all the safety and anti-inflammatory efficacy tests were carried out, it was produced on an industrial scale to be included in a cosmetic formulation and thus obtain a unique, exclusive and innovative product.


*Effects of Comano Spring Water-derived Bacterial Lysates on Skin Regeneration: An Ex-vivo Study GIOVANNI NICOLETTI 1,2,3, MARCO SALER 1,2, MARCO MARIO TRESOLDI 1,2, LAURA VILLANI 4, ERIKA MARIA TOTTOLI 5, OLIVIER JOUSSON 6,7 and ANGELA FAGA

Treatment of atopic dermatitis with probiotic L. lactis lysate - A double-blinded, placebo-controlled pilot study VILLE SALO 1, ANITA REMITZ 1, ANTTI LAUERMA 1, ALEXANDER SALAVA 1™

PROVEN EFFICACY

Lysacom Biome™ bacterial lysate has been shown* to be effective:

  • to protect the skin from damage caused by inflammation"
  • to reduce levels of skin inflammation
  • active at low concentrations​

*In vitro test on human keratocytes with psoriatic stimulation, to evaluate inflammation and cell viability

Lysacom Biome™ in Terme di Comano Skincare products

  • PSOBALANCE PRO

    SOOTHING MOISTURIZING CREAM

    An intensive-action formula for the treatment of psoriasis-prone skin. It normalizes the skin's renewal process, helps reduce redness, rebalances the lipid component, and improves the skin appearance, providing immediate comfort and relief.

    BUY NOW 

  • FROM BALANCE PRO

    NEW OCTOBER 2025

    Cosmetic adjuvant for the treatment of sensitive skin with
    atopic tendency. An exclusive treatment formulated
    to offer rapid relief and restore natural balance.

  • LONGEVITY PRO

    NEW JANUARY 2026

    A cutting-edge formula for the cosmetic treatment of blemishes related to inflammaging. It promotes skin regeneration and the production of collagen and elastin, for youthful, vibrant skin.

News from the magazine Terme di Comano Skincare

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